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herpesvirus

Kaposi Sarcoma

What is Kaposi sarcoma?

Kaposi sarcoma, sometimes called KS, is a type of cancer. It causes lesions (abnormal tissue) to grow in different parts of the body, including:

These lesions are usually red or purple. They are made of cancer cells, new blood vessels, and blood cells. The lesions may begin in more than one place in the body at the same time. This makes Kaposi sarcoma different from other cancers.

What causes Kaposi sarcoma and who is more likely to develop it?

Kaposi sarcoma is caused by infection with human herpesvirus-8 (HHV-8). This virus is also called Kaposi sarcoma-associated herpesvirus (KSHV). Most people infected with this virus don't get Kaposi sarcoma. But certain people who get this virus are more likely to develop one of the types of Kaposi sarcoma:

What are the symptoms of Kaposi sarcoma?

Kaposi sarcoma usually starts out as one or more red, purple, or brown skin lesions on the legs and feet. They are most often on the ankles or soles of the feet. Over time, lesions may form in other parts of the body. The lesions may not cause symptoms. But sometimes the lesions can cause problems, especially as you get more of them and they grow bigger. For example:

How is Kaposi sarcoma diagnosed?

To find out whether you have Kaposi sarcoma, your health care provider:

If you do have Kaposi sarcoma, you will likely need blood and imaging tests to find out if the cancer has spread to other parts of the body.

What are the treatments for Kaposi sarcoma?

Which treatment(s) you get will depend on

For people who have epidemic (HIV-associated) Kaposi sarcoma, taking HIV medicines may be enough to treat the Kaposi sarcoma. For people who have iatrogenic (transplant-related) Kaposi sarcoma, changing the dose of the medicines or switching medicines may be helpful. But some people with these types of Kaposi sarcoma will need additional treatment.

The treatment options for Kaposi sarcoma may include:

NIH: National Cancer Institute

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